Choosing initial therapy for hypertension. A personal view.

Choosing initial therapy for hypertension. A personal view.

With numerous safe and effective antihypertensive drugs now available, the clinician should no longer choose only diuretic agents or beta-adrenergic receptor blockers (beta-blockers) as initial therapy. Five classes of agents, including angiotensin converting enzyme inhibitors, beta-blockers, calcium entry blockers, peripheral alpha 1-adrenergic receptor blockers, and thiazide diuretic agents, ...

Choosing Initial Therapy for Hypertension

With numerous safe and effective antihypertensive drugs now available, the clinician should no longer choose only diuretic agents or /3-adrenergic receptor blockers (/3-blockers) as initial therapy. Five classes of agents, including angiotensin converting enzyme inhibitors, /3-blockers, calcium entry blockers, peripheral a,-adrenergic receptor blockers, and thiazide diuretic agents, are all app...

Choosing Initial Antiretroviral Therapy: Current Recommendations for Initial Therapy and Newer or Investigational Agents.

There is general consistency among US and European guidelines regarding the initiation of antiretroviral therapy for HIV-infected individuals. Recent and ongoing trials comparing regimens may lead to reevaluation of initial treatment choices. The choice of antiretroviral regimen will also likely be affected by development, evaluation, and availability of newer drugs. This article reviews curren...

Scrapie--a personal view.

Copulas: A personal view

Copula modeling has taken the world of finance and insurance, and well beyond, by storm. Why is this? In this paper I review the early start of this development, discuss some important current research, mainly from an applications point of view, and comment on potential future developments. An alternative title of the paper would be “Demystifying the copula craze”. The paper also contains what ...